Foundayo (orforglipron) received FDA approval on April 1, 2026. It's the first oral GLP-1 you can take any time of day without food or water restrictions. Self-pay starts at $149/month; insured patients may pay $25/month with a savings card.
How to Get Prescribed
Foundayo prescriptions are available through your existing doctor, telehealth platforms, LillyDirect, and retail pharmacies nationwide. The eligibility criteria are standard: BMI 30+ or BMI 27+ with at least one weight-related condition.
What Makes It Different
| Feature | Foundayo | Injectable GLP-1s |
|---|---|---|
| Administration | Daily pill, any time | Weekly injection |
| Food restrictions | None | N/A |
| Avg weight loss | ~11-12% | 15-21% |
| Self-pay | $149-399/mo | $99-1,349/mo |
| Refrigeration | No | Yes (injectable) |
The Titration Schedule
Foundayo follows a structured dose escalation: 0.8mg → 2.5mg → 5.5mg → 9mg → 14.5mg → 17.2mg, increasing approximately every 4 weeks. Most patients reach their maintenance dose within 4-6 months.
Who It's Best For
Foundayo is ideal if you strongly prefer pills over injections, have commercial insurance (savings card brings cost to $25/mo), want an FDA-approved medication with standardized manufacturing, or travel frequently and can't manage cold-chain shipping for injectables.
If maximum weight loss is your priority and cost is secondary, injectable semaglutide or tirzepatide through telehealth remains more effective.
Review consultation options, program fees, medication access, insurance considerations and what happens after your first appointment.
Explore Sesame Care ↗Eligibility and prices must be verified directly. Compounded GLP-1 products are not FDA-approved.Review its telehealth eligibility process, treatment options, follow-up care and recurring charges.
Explore Oak GLP-1 ↗Medication, legal availability, provider credentials and full price require verification; compounded medications are not FDA-approved.⚕️ Compounded medications are not FDA-approved. They are prepared by licensed pharmacies under physician supervision.