Sesame Care GLP-1 Review: How the Marketplace Weight-Loss Program Works and What You'll Really Pay

Sesame Care is a cash-pay healthcare marketplace where independent, licensed clinicians list their services and set their own prices. Its weight-loss program, Success by Sesame, pairs you with one of those clinicians for ongoing care, then prescribes brand-name GLP-1s if appropriate. Care and medication are two separate bills, and understanding that split is the key to what you'll pay.

We haven't been patients. This review is built from Sesame's published program pages, medication pages, membership page, Terms of Service, and the regulatory records we could check as of October 29, 2026. Sesame's prices vary by provider, so confirm yours before you book.

How Sesame's GLP-1 program works

Sesame isn't a telehealth clinic in the usual sense. Its Terms describe it as a platform that facilitates the sale of care by independent providers who are "not employees nor contractors of Sesame." Sesame, Inc. is based in New York and, per Fierce Healthcare, launched in 2019 as a two-sided marketplace for primary care, specialists, labs, and imaging. It has partnered with Costco to offer its weight-loss program to Costco members.

The weight-loss program runs in five steps, according to Sesame's program page:

1. Questionnaire and provider choice. You answer a short intake and pick a clinician from the marketplace.
2. Video visit. The provider builds a plan and may order labs if metabolic data is needed.
3. Prescription, if appropriate. You can pick up medication same-day at a local pharmacy or have it delivered.
4. Start treatment. The Sesame app logs doses and side effects.
5. Ongoing care. Video follow-ups, provider messaging, weight tracking, and diet, sleep, and exercise tools.

Because you choose a specific clinician, you can read their profile before booking. The flip side is that experience can vary from provider to provider in a way it doesn't at a single-clinic brand.

What the program costs

The care fee

Sesame's program page lists care at $59 a month, with a footnote tying that price to a 12-month Success by Sesame commitment. Its Wegovy page repeats the $59 figure for an annual subscription. Its Zepbound page says the subscription starts at $99 a month, and the program page's own meta description also says $99. Sesame says providers set their own prices, so some charge more than the starting figure.

Per the program page, the care fee covers your chosen provider, video visits and messaging, labs to monitor progress, same-day prescriptions and refills, and the app. It does not include medication.

The medication bill

Medication is paid separately and only if prescribed. Sesame's pages list mostly manufacturer self-pay prices, with the prescription sent to the drugmaker's own pharmacy:

Sesame's Wegovy page says the self-pay offer is for new U.S. self-pay patients, excludes anyone enrolled in a federal or state program with drug coverage, and runs through December 31, 2026. Ozempic, Mounjaro, and Rybelsus appear in Sesame's menus without prices.

Insurance and Sesame Plus

Sesame's care is cash-pay, and its Terms say those payments don't count toward insurance out-of-pocket limits. Medication is different: Sesame's medication pages say your plan may cover some or all of the drug, list insurance prices "as little as $25/mo" depending on plan, and say Sesame providers can help with prior authorization paperwork.

Sesame also sells a separate membership, SesamePlus, at $10.99 a month or $99 a year. It takes $10 off many visits and includes one free lab test a year (not in Washington State). Its page doesn't list any weight-loss program or medication discount, so it's optional for GLP-1 patients.

Commitment, cancellation, and refunds

This is the weakest part of Sesame's disclosures. The program pages tie the $59 price to a 12-month commitment, but none of the weight-loss pages we read spell out how to cancel, whether there's an early-termination charge, or what's refundable.

Sesame's Terms of Service do cover its subscription memberships in general:

• Subscriptions renew automatically until canceled.
• You can cancel up to 48 hours before the renewal processing date, by email or phone.
• Canceling doesn't earn a prorated refund; access continues through the current term.
• If you leave a multi-month plan early, Sesame recalculates it at the standard monthly rate for the months you used and may refund the remainder, though in some cases no refund is issued.
• For prescription services, the first prescription can't be canceled or refunded.

Whether those rules apply word for word to Success by Sesame isn't stated. Before you accept a 12-month price, ask support in writing what happens if you stop at month three. Disputes go to binding AAA arbitration under New York law.

Pharmacy, states, and regulatory checks

Pharmacy

Sesame's Terms say it is "not a pharmacy" and names Truepill as its delivery pharmacy partner. Its medication pages route cash-pay Wegovy to NovoCare and Zepbound vials and KwikPens to LillyDirect, or you can use a local pharmacy for same-day pickup. Because the medications are FDA-approved brand-name products, you're not relying on an unnamed compounder.

States

Sesame's weight-loss pages don't list states. Each clinician can only treat patients where they're licensed, so availability depends on who practices in your state. Fierce Healthcare reported the Costco weight-loss program as available in all 50 states; check the marketplace for your own location.

LegitScript and FDA

• FDA: We found no FDA warning letter naming Sesame, Inc. in the FDA's database or in coverage of the March 2026 letters to telehealth firms over compounded GLP-1 marketing. Sesame's weight-loss pages don't list compounded drugs, which those letters targeted.
• LegitScript: We didn't confirm a LegitScript certification for Sesame. You can search it on legitscript.com.

Red flags and things to verify

• Two different care prices. $59 and $99 both appear as the starting price. Find out which one your provider charges and on what term.
• Big headline claim. The program page says you can "lose up to 25% of your body weight" without tying the figure to a specific drug or trial.
• Missing program terms. No published cancellation or refund policy specific to the weight-loss subscription.
• Provider variability. Prices, visit style, and responsiveness depend on the clinician you pick.

Our telehealth red flags list covers other warning signs to check for any provider.

Who Sesame is best for

Sesame is a weaker fit if you want compounded medication, one all-in monthly price, or a single clinic with uniform service.

Alternatives and next steps

• Skip the middle layer? If you already have a prescriber, you can use LillyDirect or NovoCare directly.
• Want all-in pricing? Compare programs in our 15-provider cost comparison and best telehealth platforms guide.
• Insured? Check whether your plan covers these drugs first with our insurance coverage guide.

1. Add both bills. Care fee plus the medication price at the dose you'll likely reach.
2. Ask about the term. Get the cancellation and refund rules for Success by Sesame in writing.
3. Check the provider. Read their profile, price, and state license before booking.
4. Know the red-flag symptoms. Severe stomach pain that won't ease, repeated vomiting, or signs of an allergic reaction need urgent in-person care.

Dose decisions belong to your prescriber. If Sesame fits, the buttons below go to its Zepbound and Wegovy pages.